No more than 2 films should be placed on the inside of one cheek at the same time. Drink water to moisten your mouth before taking the film to help it dissolve better. Do not cut, chew, or swallow the film. The amount of buprenorphine may be different than other buprenorphine containing medicines and your doctor will prescribe a starting dose that is right for you. Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication.
You may also ask a family member or a friend to remind you or check in with you to be sure you are taking your medication. Do not double your next dose or take more than what is prescribed. They may increase adverse effects e. Keep in mind that some cough syrups may contain opioid pain medication. If an overdose occurs, call your doctor or You may need urgent medical care. You may also contact the poison control center at You should always call after giving someone naloxone to treat an overdose.
Ask your provider if naloxone is right for you. Buprenorphine is a partial opioid agonist. Like other opioids, buprenorphine causes physical dependency when taken daily for a long period of time. These medications should be taken exactly as prescribed. This medication has an opiate drug in it. The FDA has found that the use of opiate drugs with benzodiazepine drugs or other sedating medications can result in serious adverse reactions including slowed or difficult breathing and death.
Benzodiazepine drugs include drugs like alprazolam, clonazepam, and lorazepam. Benzodiazepine drugs are used to treat health problems like anxiety, trouble sleeping, or seizures. Patients taking opioids with benzodiazepines, other sedating medications, or alcohol, and caregivers of these patients, should seek immediate medical attention if they start to experience unusual dizziness or lightheadedness, extreme sleepiness, slowed or difficulty breathing, or unresponsiveness.
Last Updated: January This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists.
This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions.
Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein. Search Close Menu. Sign In About Mental Illness. About Mental Illness Treatments. About Mental Illness Research. Your Journey Individuals with Mental Illness.
Buprenorphine is the first medication to treat OUD that can be prescribed or dispensed in physician offices, significantly increasing access to treatment. Practitioners utilizing this exemption are limited to treating no more than 30 patients at any one time time spent practicing under this exemption will not qualify the practitioner for a higher patient limit. An eligible provider may choose to undertake training, or forego it prior to prescribing buprenorphine.
As noted above, those who forego training are limited to treating no more than 30 patients at any one time. Several federal laws and regulations permit physicians and other medical personal to administer medications approved by the Food and Drug Administration FDA for the treatment of opioid use disorders OUD under special circumstances without a buprenorphine waiver.
Learn about these special circumstances. Buprenorphine offers several benefits to those with OUD and to others for whom treatment in a methadone clinic is not appropriate or is less convenient. Refer to the individual product websites for a complete listing of drug interactions, warnings, and precautions.
Buprenorphine is an opioid partial agonist. It produces effects such as euphoria or respiratory depression at low to moderate doses. With buprenorphine, however, these effects are weaker than full opioid agonists such as methadone and heroin.
When taken as prescribed, buprenorphine is safe and effective. Buprenorphine has unique pharmacological properties that help:. Patients diagnosed with an OUD should talk to their health care practitioner before starting treatment with buprenorphine to fully understand the medication and other available treatment options.
These are not all the side effects of buprenorphine. For more information patients should talk to their health care practitioner or pharmacist.
Patients should tell their health care practitioner about any side effects that are bothersome, or do not go away. Learn about other MAT medications. Buprenorphine may be prescribed to women who are pregnant and have an OUD. Buprenorphine and methadone are considered the treatments of choice for OUD in pregnant and breastfeeding women.
Buprenorphine has a long half-life, generally staying in the system for at least 24 hours, as well as a ceiling effect, meaning that after a certain point you will cease to receive any benefit from taking it.
This can create quite a shock and may be very uncomfortable. The naloxone in Suboxone is a partial opioid antagonist as well, which is often used to reverse opioid overdose side effects and can also cause precipitate withdrawal. This part of Suboxone is more of an abuse deterrent, preventing potential diversion and abuse.
Mixing alcohol or other drugs with Suboxone may also cause precipitated withdrawal. It is important to be honest about your last dose of an opioid drug when seeking treatment for opioid abuse as well. Suboxone is effective for use starting in early withdrawal, during what is called the induction phase of medically assisted opioid addiction treatment. When used as directed, and at the right point during treatment, Suboxone can be a very effective tool for managing opioid withdrawal symptoms and cravings.
Generally speaking, the more physically dependent someone is on a drug, the longer it may take for the drug to leave their system, which means they might take Suboxone too soon and suffer from precipitated withdrawal. Precipitated withdrawal symptoms may be more intense and have a much faster onset than regular opioid withdrawal. Symptoms of both withdrawal and precipitated withdrawal may include:.
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